ISSN 1662-4009 (online)

ey0016.2-10 | Gestational Diabetes Mellitus: Neonatal and Long-term Consequences | ESPEYB16

2.10. Association of gestational diabetes with maternal disorders of glucose metabolism and childhood adiposity

WL Jr Lowe , DM Scholtens , LP Lowe , A Kuang , M Nodzenski , O Talbot , PM Catalano , B Linder , WJ Brickman , P Clayton , C Deerochanawong , J Hamilton , JL Josefson , M Lashley , JM Lawrence , Y Lebenthal , R Ma , M Maresh , D McCance , WH Tam , DA Sacks , AR Dyer , BE Metzger , Follow-up Study Cooperative Research Group HAPO

JAMA. 2018 Sep 11;320(10):1005–1016. doi: 10.1001/jama.2018.11628.The aims of this study were to assess whether in utero exposure to untreated gestational diabetes (using the IADPSG criteria) is associated with long-term risk of a disorder of glucose metabolism among mothers and greater adiposity among their children at 10 to 14 years post-partum.The Hyperglycem...

ey0020.10-8 | New Drugs for Children with T2DM | ESPEYB20

10.8. Outcomes in children of women with type 2 diabetes exposed to metformin versus placebo during pregnancy (MiTy Kids): a 24-month follow-up of the MiTy randomised controlled trial

DS Feig , JJ Sanchez , KE Murphy , E Asztalos , B Zinman , D Simmons , AM Haqq , IG Fantus , L Lipscombe , A Armson , J Barrett , L Donovan , P Karanicolas , S Tobin , K Mangoff , G Klein , Y Jiang , G Tomlinson , J Hamilton , MiTy Kids Collaborative Group Hamilton

Brief summary: MiTy Kids is a prospective cohort study of children who were exposed to metformin during pregnancy. At 24 months, no difference was observed between those exposed to metformin and a placebo group, in BMI trajectories, mean BMI Z-score, or mean sum of skinfolds. Among those exposed to metformin, the BMI was higher among males than females.Comment: Metformin is increasingly used during pregnancy in women with T2D, but data on its lo...